In addition to cultured cells, fresh cells are administered either via local injection or intravenous infusion.

1.Fresh Cells
（Fresh Cells: Freshly harvested stem cells)
2.Cultured Cells
（Cultured Cells: Culture-expanded stem cells)

Medical Treatment: Two Types of Stem Cell Therapy

1.Fresh Cell Therapy
Fresh stem cells are extracted from approximately 100 cc of adipose tissue harvested under local anesthesia.
These cells are administered on the same day either:
by local injection into the affected area (e.g., joints), or
via intravenous infusion (IV drip).
This procedure is performed on an outpatient basis (same-day surgery).
2.Cultured Cell Therapy
A portion of the fresh cells is cryopreserved and cultured in our in-house Cell Processing Center (CPC).
Approximately one month after the start of culture, the cultured cells are administered either:
by local injection into the affected area (e.g., joints), or
via intravenous infusion.

Following the initial fresh cell treatment, cultured cell therapy is provided periodically based on the patient’s clinical condition.

Indications / Conditions

1.Osteoarthritis
2.Rheumatoid arthritis (refractory cases)
3.Residual numbness or pain in the upper or lower limbs due to spinal disorders or cerebrovascular diseases (including persistent symptoms after surgery)
4.Chronic pain remaining after standard treatments or surgical interventions
5.Injuries of muscles, tendons, ligaments, and other periarticular tissues

Providing Medical Institution

SOBAJIMA CLINIC

〒577-0011
Clinic court Higashino, 2-2-6 Aramoto-kita, Higashi Osaka City

https://sobacli-saisei.com/

Specialty

【Departments / Services】
Orthopedics (General)
Sports Orthopedics
Regenerative Medicine (Osteoarthritis)
Stroke & Lifestyle-related Diseases
Dementia
Rehabilitation
Breast Clinic
Various MRI Examinations

【Health Checkups】
Whole-body MRI Cancer Screening (DWIBS)
Painless Breast MRI Screening (DWIBS)
Brain Checkup (Head MRI & MRA)
Brain Checkup (Head MRI & MRA + Neck MRA)
Head & Cervical Spine Checkup
Breast Cancer Screening (Mammography + Breast Ultrasound + Physical Examination + Consultation)
Spine Checkup (Cervical & Lumbar MRI)
Osteoporosis Checkup (Thoracic & Lumbar MRI + Bone Density Test)
Brain Checkup with AI-based Dementia Risk Assessment

【Treatments】
PRP Therapy for Orthopedic Conditions
Extracorporeal Shockwave Therapy
Stem Cell Therapy (Orthopedic Conditions)
Stem Cell Therapy for Chronic Pain (e.g., numbness from spinal canal stenosis)
Stem Cell Therapy for Post-stroke Sequelae

Eligibility Criteria/Exclusions for Treatment

Contraindications (Not Eligible for Treatment) Patients who meet any of the following conditions are not eligible for treatment: • Patients receiving dual antiplatelet therapy • Patients for whom temporary discontinuation of antiplatelet agents is not possible • Patients who are deemed unsuitable for treatment based on preoperative evaluation by a physician

Remarks

【Program Introduction Video】 https://www.youtube.com/@そばじまクリニック 【Treatment Schedule】 Initial consultation and various examinations are conducted to determine treatment eligibility (approximately 1–2 weeks). If eligibility is confirmed, the patient will choose between fresh cell therapy or cultured cell therapy. [In the Case of Fresh Cell Therapy] Adipose tissue is harvested under local anesthesia, and fresh cell therapy is performed. The procedure is carried out on an outpatient basis (same-day surgery), followed by regular follow-up evaluations. At the time of administration, a portion of the cells is cryopreserved in advance. [In the Case of Cultured Cell Therapy] Adipose tissue is harvested under local anesthesia. Cultured cells are prepared over approximately one month in our in-house Cell Processing Center (CPC). On the scheduled treatment day, the patient will visit the clinic to receive either local injection or intravenous infusion of the cultured cells. [From the Second Treatment Onward] After the initial treatment with either fresh cells or cultured cells, regular follow-up visits are conducted to monitor progress and determine the need for additional treatments. Subsequent treatments are performed using cultured cells. A waiting period of at least one month is required after the treatment decision, as time is needed for cell culture preparation.

Precautions / Contraindications

Understanding of the Safety and Efficacy of This Regenerative Medical Treatment