*Cell Reverse（Autologous Cultured dermal fibroblast transplantation）

Cell Reverse (fibroblast culture transplantation) is a regenerative therapy in which fibroblasts are extracted from a small skin sample taken from behind the patient’s ear, cultured using the patient’s own serum to approximately 100,000 times, and then injected into the skin.

This treatment promotes the regeneration of collagen, elastin, and hyaluronic acid, helping restore skin firmness, elasticity, and hydration. It activates and increases fibroblasts weakened by aging and UV damage, aiming for fundamental skin quality improvement.

In addition to anti-aging purposes, it is also indicated for conditions such as dermal atrophy caused by long-term steroid use or atopic dermatitis, photoaging due to excessive UV exposure, and weakened skin structure and elasticity.

Furthermore, the cultured cells can be cryopreserved at -196°C for long-term storage and reused when needed.

Providing Medical Institution

D front clinic

〒108-0075
Orix Shinagawa building 6F,2-5-3, Kounan, Minato-ku, Tokyo

http://dfront.jp/

Specialty

Cosmetic delmatology

Eligibility Criteria/Exclusions for Treatment

Patients using a wheelchair are eligible if they can remain in a supine position for approximately 1 hour.

Remarks

【Treatment Schedule】 ①Consultation ②Infectious disease blood test (approx. 30 minutes) 　→ Results available in about 1 week. If all results are negative, proceed to step 3 ③Skin and blood collection (approx. 1 hour) 　→ Followed by initial cell culture (about 5 weeks), then proceed to step 4 ④First skin cell transplantation (approx. 2 hours) 　→ Proceed to step 5 within 3 days to 2 weeks ⑤Second skin cell transplantation (approx. 2 hours)

Precautions / Contraindications

Patients who meet any of the following conditions may not be eligible for this treatment, or the cells may not proliferate sufficiently:

(1) Positive results in infection screening tests designated by our clinic
(2) Pregnant or possibly pregnant
(3) History of hypersensitivity to human insulin
(4) History of hypersensitivity to antibiotics (including β-lactamase inhibitor combinations) or other medications
(5) Patients who have undergone blood purification therapy within the past 6 months or are currently on dialysis
(6) Any other condition deemed unsuitable by the attending physician