Our medical facility is located in Kojimachi, Chiyoda-ku, Tokyo, a central area home to Japan’s core institutions, including parliamentary facilities.
We are fully equipped to provide comprehensive medical services ranging from treatment to preventive care, not only to domestic patients but also to international visitors, including foreign patients visiting Japan for health management.
Our entire team is committed to providing each and every visitor with accurate, evidence-based medical solutions and heartfelt care. Through sincere and compassionate service, we aim to realize the full potential of advanced Japanese medicine and promote personalized care that contributes to extending healthy life expectancy.

We have established a comprehensive healthcare system capable of providing a full range of medical services—from disease treatment to preventive medicine—not only for domestic patients in Japan, but also for international patients visiting Japan for medical care and health management purposes.

Our medical team is committed to delivering the most accurate, evidence-based, and patient-centered medical solutions to every individual who visits our clinic. By sincerely supporting each patient and promoting personalized medicine that contributes to healthy longevity, we strive to provide advanced Japanese medical care of the highest standard.

Location
1-minute walk from Exit 2 of Kojimachi Station (Tokyo Metro Yurakucho Line)
9-minute walk from the Kojimachi Exit of Yotsuya Station (JR Chuo Line)
Medical Services

Insurance-Covered Medical Care

General Internal Medicine
Rheumatology

Private Medical Services

Comprehensive Cancer Treatment (including Immunotherapy Supportive Treatments)
Preventive Medicine and Health Screening
Anti-Aging Medicine and Related Services
Medical Equipment
Ankle-Brachial Index (ABI) Vascular Age Assessment System
Extracorporeal Circulation System (Apheresis)
Other advanced medical equipment
Clinical Experience

Clinic Cases

Solid Tumors: Over 300 cases

Cumulative Clinical Experience

Fibromyalgia: Over 150 cases
Interstitial Lung Disease: Over 700 cases
Autoimmune Diseases: Over 300 cases

Location

〒102-0083
2nd Floor, Kojimachi Shimura Building, 4-1-5 Kojimachi, Chiyoda-ku, Tokyo

Website

https://www.jtkclinic.com/

Specialty

(Disease) Chronic Pain, Fibromyalgia
(Disease) Lifestyle-Related Diseases (Hypertension, Diabetes Mellitus, Dyslipidemia)
(Disease) Selected Autoimmune Diseases (e.g., Systemic Lupus Erythematosus)
(Disease) Various Solid Tumors
(Therapy / Procedure) Blood Purification Therapy Using LDL Apheresis (for Hypercholesterolemia and Atherosclerosis)
(Therapy / Procedure) Immune Cell Infusion Therapy (for Various Solid Tumors)
(Therapy / Procedure) Stem Cell Therapy (for Chronic Pain)　
(Treatment / Procedure)iPS Cell-Derived Exosome Therapy (Intravenous Infusion, Intranasal Administration, Intra-Articular Knee Injection, and Inhalation Therapy)　　　　　　　　　　　

Third-party certification

November 2024: Certified as the Most Trusted International Organization by Chinese Patients (2024)

December 2024: Accredited as a Registered Guarantor for Medical Stay Visas

Other Certifications

Certified as the Most Trusted International Hospital by Chinese Patients (Fiscal Year 2024) Designated as a Core Medical Institution for Accepting Foreign Patients Accredited as a Registered Guarantor for Medical Stay Visas (Registration No.: B-219)

Facility details

Our medical facility is located in Kojimachi, Chiyoda-ku, Tokyo—a central area where Japan’s core institutions, including parliamentary facilities, are concentrated.
We are fully prepared to provide a comprehensive range of medical services, from treatment to preventive care, not only to domestic patients but also to international visitors to Japan seeking health management.
With a sincere and patient-centered approach, our entire staff is dedicated to delivering the most accurate and evidence-based medical solutions, along with heartfelt care. We aim to realize the full potential of advanced Japanese medicine and promote personalized care that contributes to healthy longevity.

[Treated Conditions and Case Volume]

Solid tumors: 300 cases (as a clinic)

Fibromyalgia: 150 cases

Interstitial pneumonia: 700 cases

Autoimmune diseases: 300 cases (cumulative total)

Available Programs

• NMN・NAD+点滴【医療法人社団知慎会　JTKクリニック】

  This health management program incorporates NMN and NAD+ through intravenous infusion, with the goal of supporting cellular energy metabolism, overall wellness, and physical condition maintenance.

  NMN and NAD+ Infusion Therapy is a health management program focused on compounds that are believed to decline with age, with the aim of supporting cellular energy metabolism and maintaining overall physical well-being. In recent years, NMN and NAD+ have attracted growing interest in the field of healthy aging and wellness. They are often sought by individuals concerned about fatigue, disrupted daily routines, or age-related declines in physical and mental performance. Through this program, we propose a novel approach to everyday health maintenance by supporting physical condition and well-being from within the body.

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• Dental Pulp Stem Cell-Derived Exosome Intravenous Infusion Therapy 【JTK Clinic, Chishinkai Medical Corporation】

  This regenerative medicine program utilizes intravenous administration of dental pulp stem cell-derived exosomes with the goal of supporting overall physical condition and well-being.

  Dental Pulp Stem Cell-Derived Exosome Infusion Therapy is a regenerative medicine program that utilizes intravenous administration of exosomes derived from dental pulp stem cells, with the aim of supporting overall physical condition and wellness. In recent years, exosomes have attracted considerable attention in the field of regenerative medicine and are increasingly being incorporated into health management, healthy aging, and daily wellness support programs. Through this program, we aim to support modern health management from a new cellular-level perspective, while placing importance on patient comfort and minimizing physical burden.

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• iNK Immune Cell Therapy 【JTK Clinic, Chishinkai Medical Corporation】

  This NK immune cell therapy program is designed to support a wide range of goals, from immune management for patients with cancer to general health maintenance and healthy aging through immune system support.

  iNK Immune Cell Therapy is a program that utilizes Natural Killer (NK) cells with the goal of supporting and optimizing the body's immune environment. While it may be incorporated as part of immune condition management for patients with cancer, there has also been growing interest in its use among healthy individuals seeking support for healthy aging and everyday wellness. This immune-based approach is attracting attention across a wide range of age groups, not only as a strategy for addressing health concerns after illness develops, but also from the perspective of maintaining long-term health through proactive immune management.

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• iPS Cell-Derived Exosome Inhalation Therapy 【JTK Clinic, Chishinkai Medical Corporation】

  This regenerative medicine program utilizes inhaled iPS cell-derived exosomes with the goal of supporting respiratory function and overall physical condition management.

  The iPS Cell-Derived Exosome Inhalation Program utilizes inhalation as a low-burden delivery method, making it easy to incorporate into daily life and suitable for ongoing use. In recent years, research into exosomes has expanded across a variety of fields, including support for respiratory function and overall health management. At our clinic, we combine perspectives from regenerative medicine, functional medicine, and preventive medicine to provide personalized recommendations tailored to each individual's health status and goals. We place strong emphasis on pre-treatment consultation with the attending physician and have established a treatment framework that prioritizes safety and continuity of care. We also offer support in Japanese, Chinese, and English, enabling us to assist not only patients residing in Japan but also those seeking consultation from overseas. Our goal is to make advanced regenerative medicine more accessible and approachable for a wider range of individuals.

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• iPS Cell-Derived Exosome Intra-Articular Knee Injection Therapy【 JTK Clinic, Chishinkai Medical Corporation】

  This regenerative medicine program involves the injection of iPS cell-derived exosomes into the knee joint, with the goal of supporting the management of inflammation and the maintenance of joint function.

  The iPS Cell-Derived Exosome Knee Injection Program is attracting attention as an emerging approach in the field of regenerative medicine. By delivering iPS cell-derived exosomes directly into the knee joint, the program is intended to support inflammation management and help maintain joint function in individuals experiencing age-related discomfort, joint stress, or reduced mobility. At our clinic, we integrate perspectives from regenerative medicine, functional medicine, and preventive medicine to provide personalized recommendations tailored to each patient's condition, lifestyle, and goals. We frequently receive consultations from individuals who wish to maintain independent mobility for as long as possible or continue participating in sports and recreational activities. We place strong emphasis on pre-treatment consultation with the attending physician and maintain a clinical framework designed with careful consideration for both safety and continuity of care. Support is available in Japanese, Chinese, and English, enabling us to assist both domestic and international patients. Our goal is to provide an environment where patients can seek consultation with confidence and explore advanced regenerative medicine options in a safe and supportive setting.

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• iPS Cell-Derived Exosome Intranasal Therapy【 JTK Clinic, Chishinkai Medical Corporation】

  This next-generation program utilizes intranasal administration of iPS cell-derived exosomes and is designed to support neurological health management while exploring potential applications in the field of regenerative medicine.

  The iPS Cell-Derived Exosome Intranasal Program is attracting attention as an emerging approach in the field of regenerative medicine. By utilizing a non-invasive intranasal administration method, the program is designed to minimize disruption to daily life while offering a convenient option that may be incorporated into ongoing health management. In recent years, research has expanded both in Japan and internationally regarding the potential applications of exosomes in areas such as neurological health management and the maintenance of physical condition associated with aging. At our clinic, we integrate perspectives from regenerative medicine, functional medicine, and preventive medicine to provide individualized recommendations based on each patient's health status and goals. We welcome consultations not only from patients residing in Japan but also from those visiting from overseas. Support is available in Japanese, Chinese, and English, enabling us to provide comprehensive assistance throughout the consultation and treatment process.

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• iPS Cell-Derived Exosome Infusion【JTK clinic】

  Improvement of the cellular environment and anti-aging benefits (enhanced immunity, regeneration of vascular endothelial cells, activation of fibroblasts, etc.)

  iPS cells, which have the remarkable ability to differentiate into any type of cell, are being actively researched for their potential in treating various intractable diseases. This treatment involves the intravenous administration of highly concentrated exosomes—a diverse group of bioactive molecules extracted during the cultivation process of iPS cells. These exosomes help optimize the internal environment of existing cells in the body, offering a range of expected health and anti-aging benefits. By delivering genetic information-related substances directly into the body in an optimal form, this treatment may produce synergistic effects when combined with other therapies or IV drips. Due to its high compatibility with other anti-aging infusions, this course is very popular and well-received by many patients.

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• Blood Purification (LDL Apheresis Adsorption Therapy) + iPS Cell-Derived Exosome Infusion【JTK clinic】

  Arteriosclerosis
  Hypercholesterolemia

  Blood purification therapy is a treatment that removes "bad cholesterol" (LDL cholesterol), which is known as a major cause of lifestyle-related diseases such as arteriosclerosis and hypercholesterolemia, by circulating the blood outside the body using an apheresis device. By directly eliminating LDL cholesterol from the bloodstream, this therapy is expected to improve vascular endothelial function and promote better blood flow and reduction of vascular blockage. Since blood purification can help slow vascular aging (also referred to as “vascular age”), this popular treatment course aims to maximize results by following it with iPS cell-derived exosome infusion, creating a synergistic effect to further enhance therapeutic benefits.

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• Autologous Adipose-Derived Mesenchymal Stem Cell Therapy (for Chronic Pain) + iPS Cell-Derived Exosome Intravenous Infusion【JTK Clinic, Chishinkai Medical Corporation】

  Chronic pain (for those who experience persistent pain)

  This treatment involves harvesting a patient’s own adipose tissue, culturing stem cells from that tissue, and reinfusing them into the body via intravenous drip. It is designed to repair damage and degeneration in the nervous system that may be causing chronic pain. A popular course combines this stem cell therapy with iPS cell-derived exosome infusion. The transplanted stem cells are said to naturally migrate (a phenomenon known as “homing”) to areas of the body experiencing damage, degeneration, or disease, where they help repair tissue and improve the internal cellular environment, potentially leading to long-term relief from pain and even curative effects. By combining this therapy with iPS cell-derived exosomes, patients may experience enhanced activation of immune cells and fibroblasts, as well as improvements in vascular endothelial cell function—making it a highly recommended and popular regenerative treatment.

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