In 2015, N2 Clinic was founded in Daikanyama, Tokyo.
At a time when regenerative medicine was still little known to the public,
we began our journey as a specialized clinic focusing on stem cells and immune cells,
guided by a clear vision — “Pursuing true prevention and youthfulness based on science.”

In 2024, Japan became the first country in the world to enact the
Act on the Safety of Regenerative Medicine.
Through formal notification and rigorous review by the Ministry of Health, Labour and Welfare,
N2 Clinic was officially approved and has since built trust as a
fully compliant medical institution providing regenerative medicine.

In 2015, N2 Clinic was founded in Daikanyama, Tokyo.
At a time when regenerative medicine was still little known to the public,
we began our journey as a specialized clinic focusing on stem cells and immune cells,
guided by a clear vision — “Pursuing true prevention and youthfulness based on science.”

In 2024, Japan became the first country in the world to enact the
Act on the Safety of Regenerative Medicine.
Through formal notification and rigorous review by the Ministry of Health, Labour and Welfare,
N2 Clinic was officially approved and has since built trust as a
fully compliant medical institution providing regenerative medicine.

Location

〒104-0061
11th Floor, HULIC &New GINZA NAMIKI 6, 6-6-5 Ginza, Chuo-ku

Website

https://n2clinic-ginza.com

Facility Overview

In 2015, N2 Clinic was founded in Daikanyama, Tokyo.
At a time when regenerative medicine was still little known to the public,
we began our journey as a specialized clinic focusing on stem cells and immune cells,
guided by a clear vision — “Pursuing true prevention and youthfulness based on science.”

In 2024, Japan became the first country in the world to enact the
Act on the Safety of Regenerative Medicine.
Through formal notification and rigorous review by the Ministry of Health, Labour and Welfare,
N2 Clinic was officially approved and has since built trust as a
fully compliant medical institution providing regenerative medicine.

Specialty

Stem Cell Therapy

Immune Cell Therapy

Stem Cell Culture Supernatant

Available Programs

• Stem Cell Therapy【 N2 Clinic Ginza Main Branch】

  Stem cells are the key elements of regenerative medicine,
  possessing two unique abilities: self-renewal and multipotency.
  They play a vital role in repairing damaged tissues and replacing cells that have lost function due to aging.
  
  At N2 Clinic, we provide regenerative medical treatments using adipose-derived stem cells.
  A small amount of stem cells is collected from your own abdominal fat,
  then administered back into your body via IV infusion or localized injection.
  These stem cells naturally migrate to the areas in need of repair,
  promoting tissue regeneration and restoration.
  
  This treatment not only helps the body respond to age-related changes
  but is also highly valued for its aesthetic and rejuvenating effects.
  Your own cells support the future of your health and beauty.

  Stem cells are the key elements of regenerative medicine, possessing two unique capabilities: self-renewal and multipotency. They help repair damaged tissues and restore function in tissues affected by aging. At N2 Clinic, we provide regenerative medicine using adipose-derived stem cells. A small amount of stem cells is extracted from your own abdominal fat. These are then administered into the body through IV infusion or localized injection, where the stem cells naturally gather at the sites in need of repair, promoting tissue regeneration and recovery. This treatment is expected to not only counteract the effects of aging, but also bring remarkable aesthetic and rejuvenating benefits. Your own cells will support the future of your health and beauty. Treatment Process 1. Counseling A specialist will carefully listen to your concerns and explain stem cell therapy in detail. All your questions will be answered before proceeding to the next step. Duration: approximately 1 hour 2. Fat Tissue Collection A small amount of subcutaneous fat is collected from the abdomen. Since only a tiny incision is made, scarring is minimal. Local anesthesia is used to minimize pain. Duration: 1–2 hours 3. Stem Cell Isolation and Culturing The collected fat is processed at a Cell Processing Facility (CPF) to isolate and culture stem cells. First treatment: approximately 6 weeks for culturing and cryopreservation. Subsequent treatments: cells are thawed and ready for administration in about 3 weeks. 4. Stem Cell Administration According to your treatment goals, high-concentration or adjusted adipose-derived stem cells are administered. All procedures follow the official protocol approved under the Act on the Safety of Regenerative Medicine, and are performed safely under the supervision of regenerative medicine specialists. Duration: 1–1.5 hours

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• Immune Cell Therapy 【N2 Clinic Ginza Main Branch】

  Among immune cells, Natural Killer (NK) cells have the highest cytotoxic activity against cancer.
  By activating and expanding your own NK cells and administering them back into your body,
  it is possible to target cancer cells while minimizing the burden on the body.
  
  Another major advantage of this therapy is that it can be safely combined with other cancer treatments,
  enhancing overall therapeutic effectiveness.

  Among immune cells, Natural Killer (NK) cells have the strongest cytotoxic activity against cancer. By activating and expanding your own NK cells and administering them back into your body, it is possible to target cancer cells while minimizing the physical burden. Another major advantage of this therapy is that it can be safely combined with other cancer treatments. Treatment Process 1. Counseling A specialist will carefully listen to your current condition and preferences, and explain the NK cell immunotherapy in detail. All questions will be answered before proceeding to the next step. Duration: approximately 1 hour 2. Blood Collection About 30–50 ml of blood will be collected. From the second session onward, the next sample can be collected during your NK cell infusion visit, reducing the number of hospital visits. Duration: approximately 15 minutes 3. Cell Culturing The collected blood is sent to a Cell Processing Facility (CPF), where highly purified and activated NK cells are cultured over a period of 2–3 weeks. 4. Immune Cell Administration Under the protocol approved by the Ministry of Health, Labour and Welfare for regenerative medicine, the treatment is administered safely by infusion under specialist supervision. The same procedure applies to other types of immune cell therapies as well. Duration: 30 minutes–1 hour

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• Stem Cell Culture Supernatant Therapy【N2 Clinic Ginza Main Branch】

  The culture supernatant, a high-quality source of cytokines,
  can be administered either through intravenous infusion (whole-body)
  or local subcutaneous injection.
  
  Depending on your treatment goals — such as health maintenance, aesthetic enhancement,
  or tissue repair — an appropriate procedure will be recommended.

  The culture supernatant, rich in high-quality cytokines, can be administered either by intravenous infusion (whole-body) or local subcutaneous injection. Depending on your goals—health improvement, beauty enhancement, or tissue repair—the most suitable treatment will be selected. ● Health Anti-aging, improvement of cold sensitivity, vision enhancement, better sleep quality, recovery of male function, and improved blood circulation. ● Beauty When injected into the skin, it promotes skin rejuvenation and reduction of wrinkles. When applied to the scalp, it may stimulate hair growth and revitalize hair follicles. ● Local Injection The supernatant can be injected directly into areas of pain or tissue damage. At the injection site, cells become activated, promoting tissue regeneration, reducing inflammation, and relieving pain. 1. Counseling – Duration: 30 to 60 minutes 2. Administration of Stem Cell Culture Supernatant – Duration: 30 to 60 minutes (Performed via intravenous drip or local injection)

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